The Mechabol Stack - Perfect PH, Liver Support, and Aromatase Inhibitor!

• Antaeus Labs Mechabol(90 caps)
• Antaeus Labs Aegis (120 caps)
• PES Erase (90 caps)

Antaeus Labs Mechabol (Methylclostebol)

(4-chloro-17α-methyl-androst-4-en-17β-ol-3-one)

Mechabol is an Antaeus Labs take on P-Mag -- and, as such, it is a far more potent product. In all other respects it is quite similar. Like P-Mag, it does not aromatize into any estrogenic compound and has no affinity for the progesterone receptor.


(4-chloro-17α-methyl-androst-4-en-17β-ol-3-one)

Structural characteristics:

4-chloro: Completely inhibits aromatization. Reduces anabolic and androgenic potency -- but the latter more than the former, which results in a favorable anabolic/androgenic ratio.

17α-methyl: Inhibits reductive metabolism by the 17-hydroxysteroid dehydrogenase enzyme, thereby increasing oral bioavailablity.

Antaeus Labs Aegis - Liver Protection Does Not Get Stronger!

There are many types of liver injury, but only one is normally associated with the use of oral androgens -- cholestasis. This condition is defined as a failure of normal bile to reach the duodenum, which may be due to a number of different pathological states between the hepatocyte and the ampulla of Vater. When one takes oral androgens (typically methylated at C17a) the physical structure of the hepatocyte is altered -- microfilaments and canaliculi become less contractile. Disruptions in the canalicular bile salt export pump may also occur. This leads to impaired bile flow and the retention of highly cytotoxic hydrophobic bile salts. At low concentrations, these retained bile salts cause apoptosis; at higher concentrations, necrosis and severe liver damage.

This is where AEGIS comes into the picture. It was designed with users of oral androgens in mind, and brings together the best anti-cholestatic ingredients available.

Tauroursodeoxycholic acid:

-Can prevent apoptosis during cholestasis. Toxic bile acids produce apoptosis Via fas- and TRAIL- death receptor mediated pathways. Both are, to some degree, dependent on the translocation of the 'bax' pro-apoptoic molecule from the cytosol of hepatocytes to the cell mitochondria. TUDCA prevents bax translocation, strongly stabilizes mitochondrial membranes, and activates the MAPK pro-survival pathway in hepatocytes. (ref) These effects protect hepatocytes from bax-related apoptosis.

-Is a hydrophilic bile acid, and its presence markedly shifts the bile pool towards hydrophilicity, which, to some extent, detoxifies it. When used consistently, especially at pharmacological doses, TUDCA (along with UDCA) eventually becomes the predominant bile acid in the liver and in general circulation.

-Directly stimulates bile secretion via modulating cellular signalling pathways in hepatocytes, such as ERK, src, PKC and others. These signalling pathways generally phosphorylate, or activate, the bile salt export pump (BSEP) and other processes involved in bile export/secretion. (For example, PKC-alpha-mediated secretion of HCO3-.)

Polyenylphosphatidylcholine:

-Stabilizes cellular membranes and dilates bile canaliculi. This former effect has been shown to protect human cells from hydrophobic bile salt induced apoptosis, and the latter may serve to counteract the reduction in contractility seen in androgen-induced cholestasis.

-Oral androgen administration may decrease hepatic Na+, K+-ATPase, Ca2+, Mg2+-ATPase and F-actin levels --- all of which may be restored, and even raised, by polyenylphosphatidylcholine administration.

-Is secreted into bile by hepatocytes, where it serves as a major component of the micelles in which bile acids are emulsified. Increased levels of biliary phosphatidylcholine reduces the cytotoxicity of bile acids, whereas phosphatidylcholine-secretion impairment (as is often seen in ABCB4 disease) is characterized by extremely severe cholestatic liver disease.

PES Erase - The Best Anti-Estrogen Available

ERASE works through a number of different mechanisms to shift your body into a more ANABOLIC state and a less catabolic state. It is the most synergistic natural hormone modulator to hit the market!

ERASE’s ingredient is a completely DSHEA compliant natural hormone modulator that is NOT a prohormone and NOT suppressive. It is completely active and natural in its current form! It will NOT shut you down and does NOT require a Post Cycle Therapy (PCT). In fact many people will use this to recover from suppressive supplements as a PCT!
This simple yet very potent and intricate compound called Androsta-3,5-diene-7,17-dione (also known as 3-deoxy-7-oxo-DHEA) will have users experiencing all of the benefits from an increase in testosterone and reduction of high levels of estrogen and cortisol. It is a natural compound that is a downstream metabolite of DHEA that exists in the body. Erase will elevate the user’s natural anabolic state, leading to more muscle mass, better recovery, decreased fat storage, and increased libido! The first effects users notice is a drying out and hardening effect, showing increases in vascularity and increased definition.

Erase modulates your body’s natural hormone levels to improve your testosterone:estrogen ratio and testosterone:cortisol ratio. By doing this you change your body into a less catabolic state (a state of muscle breakdown) and revs you up into an Anabolic state (a muscle building state). It’s a 2 for 1!

Why do you want to lower cortisol?

Cortisol levels can rise in your body when there is an increase in testosterone, or when you stop taking anabolic supplements like prohormones. Your body does this as a natural mechanism to basically fight your increased anabolism and it does it by increasing cortisol. But you don’t want that! You want to stay anabolic!

This is what makes ERASE the most innovative and synergistic compound ever! While it will naturally increase testosterone:estrogen and testosterone:cortisol ratios, it will also allow your increased testosterone levels to give maximal effects by reducing the rise in anti-anabolic cortisol. While there is no specific data on the exact Erase compound done on the 11b-HSD enzyme, it is suspected its mechanism is similar to other 7-oxygenated DHEA compounds.

People often purchase 1 product for estrogen, 1 product for cortisol reduction, and 1 product for test boosting. Why bother? We didn’t just do this all in 1 product, but in all in one ingredient!
ERASE belongs in your supplement regimen! Whether you are bulking, cutting, recomp, on a testosterone booster, hormonal cycle, or just looking to get an edge in the gym, ERASE has its place.
Note: Some users experience mild joint pain when taking Erase. If this occurs, lower your dose by 1 capsule.