Synthetic Supplements Agmatine 500 mg
Agmatine is a novel polyamine that’s quickly gaining recognition as a powerful ergogenic. It is formed within the body after L-Arginine interacts with the enzyme arginine decarboxylase. It acts as a neurotransmitter, a precursor to the polyamines and has many other key biological functions within the body.
Agmatine is an imidazoline receptor agonist. Imidazoline receptors have several functions: regulation of insulin secretion, pain modulation, and neuroprotection/neuromodulation. Clonidine, another imidazoline receptor agonist, has been noted to stimulate the release of luteinizing hormone (LH). Researchers conducted tests on agmatine and found that it can also modulate the release of LH from its interaction with hypothalamic tissues. The modulation of imidazoline receptors by agmatine has also been shown to improve insulin sensitivity.
Agmatine is also a positive modulator of the nitric oxide synthase (NOS) pathway. Nitric oxide synthases are a group of enzymes that produce nitric oxide from the amino acid L-Arginine. Increased nitric oxide results in vasodilation, which increases blood flow, nutrient delivery to skeletal muscle, and oxygen transport.