Mentabolan Super Stack - Prohormone + Complete PCT + Liver Support

• PHF Mentabolan (150 tabs)
• PES Erase (90 capsules)
• Athletix Titanium XL (120 capsules)
• Purus Labs Organ Shield (60 capsules)

PHF Supplements Mentabolan - MENTdione is finally here!

Nomenclature:
7a-methyl-estra-4-en-3,17-dione

Anabolic/Androgenic Ratio:
960 : 165 - 510 vs testosterone by oral administration [1]

Synonyms:
7a-methyl-19-norandrostenedione, Mentabolan, MENT dione, Trestione.

History:
This is a brand new prohormone from PHF/IBE, never seen before on the prohormone or pharmaceutical market. It was synthesized and tested for anabolic and androgenic activity in rats in 1963 [1].

Function:
This is a prohormone to the black-market bodybuilding steroid and experimental contraceptive Trestolone, aka MENT. It's been described on some internet forums as "MENT dione", however since MENT is short for 7a-Methyl 19-Nor-Testosterone, this compound could more accurately be described as 7a-Methyl-19-Nor-Androstenedione, and given an acronym of it's own like MENAD or MENORAD.

Structure:
This prohormone is a "19-nor", or nandrolone derivative, and differs from nandrolone in that this hormone has a 17-ketone, where nandrolone has a 17b-hydroxy function, and also has the addition of a 7a-methyl group. In the same way as "Boladrol" is a 7a-methylated dione version of methyl testosterone, this compound is a 7a-methylated dione version of nandrolone. Please don't confuse this compound (or the target steroid) with the widely-feared mibolerone, a.k.a. "cheque drops", which is a 17a-methylated version of trestolone (or dimethylated nandrolone).

Effects:
Effects should be similar to the injectable trestolone acetate. It's a strongly anabolic, moderately androgenic compound which should elicit significant strength gains and increased accumulation of muscle mass at an appropriate dosage.

Side Effects:
Side-effects may include those common to anabolic androgenic steroids, including but not limited to: blood pressure increases, HPTA disruption, adverse shifts in lipoprotein subfractions (increased HDL, lowered LDL cholesterol), acne, hair growth or loss. This product should not be used by women or teens. There's evidence that MENT aromatizes to some degree [2], so the gyno-prone may wish to either avoid this compound or co-administer an aromatase inhibitor (AI) or selective estrogen receptor modulator (SERM).

One side-effect that many might fear from this compound is the loss of libido and/or erectile dysfunction often seen with 19-nor derivatives (known colloquially as "deca-dick"). On the contrary, tests conducted with the target hormone trestolone (MENT) have found that it had a positive mood, libido, and erection-stimulating effect similar to that of testosterone [3], though this may not necessarily hold true with the supraphysiological doses used by bodybuilders.

Metabolism and Bioavailability:
As mentioned, this is a "dione" prohormone. In the body the ketone at C17 will be hydrolysed by 17b-hydroxysteroid dehydrogenase type 1 (17b-HSD1) into the active compound trestolone (MENT). Trestolone itself has been shown to be roughly 6 times as anabolic as methyl test by oral administration, and around 2.5 times as androgenic [4].

Unlike steroids like testosterone and DHT, trestolone shows no affinity for SHBG [5], so all of the converted compound in circulation should be bioavailable. For the same reason, it's likely to have a short terminal half-life so frequent dosing is suggested.

As most will know, testosterone and similar delta-4 steroids are typically converted to stronger compounds like DHT and DHT derivatives by the enzyme 5-alpha reductase (5AR). 19-nor compounds are an exception to this rule, with 5a-reduced nandrolone (or 19-nor DHT) being a far less potent androgen than nandrolone itself [6]. The 7a-methylation of trestolone (and by extension mentabolan) hinders the reduction of this double bond, so delta 5(10) isomers are a major excreted metabolite [7]. This means that the 7a-methyl group not only makes the compound stronger by increasing androgen receptor affinity [8], but also reduces the ability of the body's enzymes to break it down into weaker metabolites.

The addition of the 7a-methyl group has a flattening effect on the molecule which improves androgen receptor binding [8]. MENT is a strong compound for several reasons (including as previously discussed steric hindrance to 5a-reduction, and an inability to bind with SHBG), but the primary reason for its strength is the increased androgen receptor affinity caused by the conformational changes of the 7a-methyl group [9]. The same will be true of the prohormone to MENT; Mentabolan.

References:
[1] Steroids 1, 299 (1963)
[2] J Steroid Biochem Mol Biol. 1994 Feb;48(2-3):297-304.
[3] J Clin Endocrinol Metab. 1999 Oct;84(10):3556-62.
[4] Acta Endocrinologica, Vol 43, Issue 3, 399-411
[5] J Androl. 1997 Jul-Aug;18(4):352-8.
[6] The Journal of Steroid Biochemistry and Molecular Biology Volume 53, Issues 1-6, 1995, 253-257
[7] Recent advances in doping analysis (12). Sport und Buch Strauß, Köln (2004) 261-268
[8] Steroids. 2009 Feb;74(2):172-97.
[9] The Journal of Steroid Biochemistry and Molecular Biology Volume 71, Issues 5-6, 1999, 213-222

PES Erase - The Best Anti-Estrogen Available

ERASE works through a number of different mechanisms to shift your body into a more ANABOLIC state and a less catabolic state. It is the most synergistic natural hormone modulator to hit the market!

ERASE’s ingredient is a completely DSHEA compliant natural hormone modulator that is NOT a prohormone and NOT suppressive. It is completely active and natural in its current form! It will NOT shut you down and does NOT require a Post Cycle Therapy (PCT). In fact many people will use this to recover from suppressive supplements as a PCT!
This simple yet very potent and intricate compound called Androsta-3,5-diene-7,17-dione (also known as 3-deoxy-7-oxo-DHEA) will have users experiencing all of the benefits from an increase in testosterone and reduction of high levels of estrogen and cortisol. It is a natural compound that is a downstream metabolite of DHEA that exists in the body. Erase will elevate the user’s natural anabolic state, leading to more muscle mass, better recovery, decreased fat storage, and increased libido! The first effects users notice is a drying out and hardening effect, showing increases in vascularity and increased definition.

Erase modulates your body’s natural hormone levels to improve your testosterone:estrogen ratio and testosterone:cortisol ratio. By doing this you change your body into a less catabolic state (a state of muscle breakdown) and revs you up into an Anabolic state (a muscle building state). It’s a 2 for 1!

Why do you want to lower cortisol?

Cortisol levels can rise in your body when there is an increase in testosterone, or when you stop taking anabolic supplements like prohormones. Your body does this as a natural mechanism to basically fight your increased anabolism and it does it by increasing cortisol. But you don’t want that! You want to stay anabolic!

This is what makes ERASE the most innovative and synergistic compound ever! While it will naturally increase testosterone:estrogen and testosterone:cortisol ratios, it will also allow your increased testosterone levels to give maximal effects by reducing the rise in anti-anabolic cortisol. While there is no specific data on the exact Erase compound done on the 11b-HSD enzyme, it is suspected its mechanism is similar to other 7-oxygenated DHEA compounds.

People often purchase 1 product for estrogen, 1 product for cortisol reduction, and 1 product for test boosting. Why bother? We didn’t just do this all in 1 product, but in all in one ingredient!
ERASE belongs in your supplement regimen! Whether you are bulking, cutting, recomp, on a testosterone booster, hormonal cycle, or just looking to get an edge in the gym, ERASE has its place.
Note: Some users experience mild joint pain when taking Erase. If this occurs, lower your dose by 1 capsule.

Purus Labs Organ Shield - Extreme Cycle Protection

Purus Labs maintains its focus on bringing you safe, anabolism-inducing product stacks by engineering the most pivotal compliment to any "pro-anabolic" cycle. Organ Shield™ was specifically designed to support hepatic (liver), prostatic (prostate), and cardiovascular (heart) function during times of high stress, such as when using "pro-anabolics." This blend of specific antioxidants, flavanoids, and phytonutrients scavenges free radicals. 365 days a year, whether ON-cycle or OFF-cycle, this is a must for any serious athletes' arsenal!

Milk Thistle
The antioxidant milk thistle has been used since Greco-Roman times. Several studies suggest milk thistle supports a healthy liver. The active component most responsible for milk thistle's detoxifying effects is called silymarin. This substance, comprised of several flavonolignands, helps support healthy liver cells.

N-Acetyl-L-Cysteine (NAC)
NAC, arguably the pinnacle antioxidant, consists of the amino acid cysteine joined with an acetyl group making it more soluble and more biovailable than L-Cysteine alone. NAC, basically a precursor to glutathione, donates cystiene to form glutathione which is found in the body and produced in the liver.

Alpha Lipoic Acid (ALA)
Alpha Lipoic Acid is quite possibly the most novel, multifaceted, and important antioxidants available today. It neutralizes free radicals in both the aqueous and lipid portions of cells, is a key player in the synergism of other antioxidants extending the metabolic life of glutathione and Coenzyme Q-10, supports a healthy liver, has blood lipid modulating properties, and supports insulin function speeding the removal of glucose from the bloodstream and ushering it into muscles.

Beta-Sitosterol
Beta-Sitosterol is one of many phytosterols, phytochemicals naturally occurring in plants, whose structure closely resembles cholesterol. Studies suggest it may help support cholesterol levels already within the normal range.

Saw Palmetto
Saw Palmetto is rich in phytosterols and fatty acids.

Quercitin
A highly active flavonoid, Quercitin, is yet another fierce antioxidant scavenging free radicals within the body.

Coenzyme Q-10 (CoQ-10)
CoQ-10 is a fat soluble, vitamin like antioxidant found in cells. The biosynthesis of CoQ-10 requires 8 other vitamins and several trace enzymes. It serves as the coenzyme for mitochondrial enzymes involved in the synthesis of ATP, which all cellular function depends. It is highly concentrated in the heart due to the high energy requirements of this muscle. It also aids in healthy cholesterol levels already in normal range.

Purus Labs Organ Shield Supplement Facts:

60 Capsules
Serving Size 2 Capsules
Servings Per Container 30

Amount Per Serving
Organ Shield Proprietary Blend:

Milk Thistle (Standardized For 80% Silymarin) 300mg
Beta-Sitosterol (Pygeum Africanum) 250mg
Saw Palmetto (Serenoa Repens) (Berries) 200mg
N-Acetyl-L-Cysteine (NAC) 250mg
Alpha Lipoic Acid (ALA) 150mg
Quercetin Dihydrate 150mg
Coenzyme Q-10 (CoQ-10) (Trans-Isomer) 100mg

Directions For Purus Labs Organ Shield: On-Cycle: Take 1 capsule twice daily with
Off-Cycle: Take up to 2 capsules twice daily.