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04.21.14

PHF Supplements Trenavar

1 tablet

90

 
Amount
Per Serving
% Daily
Value
Estra-4,9,11-triene-3,17-dione
10 mg
**

* (DV) Daily Value based on a 2,000 calorie diet

** Percent Daily Values not established.

Other Ingredients:

Maltodextrin, Magnesium Stearate, Gelatin, Silicon Dioxide

Directions:

As a dietary supplement take 3-5 tablets daily. Do not exceed 5 tablets per day.

Warnings:

Do not use if pregnant or nursing. This product is only intended for healthy adults, 18 years of age or older. Before using this product consult with your physician if you are using any prescription or over the counter medication or if you have or suspect you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication. Discontinue use and consult your health care professional if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing. Store in a cool dry place. Keep out of reach of children.

Trenavar (90 caps)

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  • Trenavar (90 caps)

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Size No
Infomation

PHF Supplements Trenavar

1 tablet

90

 
Amount
Per Serving
% Daily
Value
Estra-4,9,11-triene-3,17-dione
10 mg
**

* (DV) Daily Value based on a 2,000 calorie diet

** Percent Daily Values not established.

Other Ingredients:

Maltodextrin, Magnesium Stearate, Gelatin, Silicon Dioxide

Directions:

As a dietary supplement take 3-5 tablets daily. Do not exceed 5 tablets per day.

Warnings:

Do not use if pregnant or nursing. This product is only intended for healthy adults, 18 years of age or older. Before using this product consult with your physician if you are using any prescription or over the counter medication or if you have or suspect you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication. Discontinue use and consult your health care professional if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing. Store in a cool dry place. Keep out of reach of children.

Deal Of the Day No

PHF Trenavar - Potency Redefined! The father of Tren!


Function:

This is a prohormone to the veterinary drug and black-market bodybuilding steroid trenbolone. Unlike previous "tren" prohormones, this one actually converts in the body to trenbolone. Previous "tren" PHs converted to the structurally similar - but markedly weaker - steroid dienolone.

Structure:

This prohormone has the same three conjugated double bonds as trenbolone, and differs from it only in that this hormone has a 17-ketone, where trenbolone has a 17b-hydroxy function. In the body this ketone will be readily hydrolysed by 17b-hydroxysteroid dehydrogenase type 1 (17b-HSD1) into the active form, trenbolone.

Effects:

Conversion to trenbolone should be high, so effects should be identical to the injectable form - with the exception of the famed "tren cough". Whatever the explanation for "tren cough" (and many have been suggested), since it's a reaction to the sudden parenteral introduction of some compound directly into the body, it's highly unlikely that any orally administered compound will have the same effect.
Trenbolone is one of the strongest injectable steroids on the market, so effects experienced from Trenavar can be expected to be largely the same - huge strength and size increases, accelerated fat loss, and enhanced vascularity.

Side Effects:

Blood pressure is likely to be dose-dependently elevated to a significant degree, cholesterol levels and liver function markers are likely to be adversely affected, though to what extent remains to be seen. Commonly reported trenbolone sides include night-sweats, mood swings, androgenic hair loss and/or growth, temporary loss of libido, as well as the suppression of endogenous testosterone production, and it would be sensible to assume that these may also result from use of Trenavar.

Metabolism and Bioavailability:

Warning: if you're not interested in advanced steroid metabolism discussion, skip over this section. If you want solid info on how and why an oral tren PH should work, read on.

The anabolic effects of trenbolone are due in part to the enhanced androgen receptor binding that the conjugated double bond system causes [1], and also because trenbolone is an antagonist of the glucocorticoid receptor [2]. The double bonds extending up the backbone of the steroid flattens the steroid considerably, which makes it an excellent fit for the androgen receptor. It also makes the molecule much more flexible, and therefore less receptor-specific [3]. Trenbolone is incapable of being affected by 5a-reductase, 5b-reductase, or aromatase. But will it work orally?

The first place to turn to for information on steroids is the seminal 1969 work Androgens and Anabolic Agents by Julius Vida. Unfortunately this compound isn't among the 666 compounds discussed there, and there's a shortage of information on trenbolone by oral adminstration. I was fortunate enough to find a study which compared the anabolic effects of oral and subcutaneous application of trenbolone in rats [4], and the results were frankly startling. They found that to have a comparable anabolic effect, trenbolone needed to be administered orally at 100 times the dosage as when administered by subcutaneous injection (see graph). Sounds pretty bad for a tren PH then, right? Well, the good news is we're not rats.

Trenbolone is metabolised differently in different species - in rats, around 40% is excreted as a dione form, as well as several metabolites hydroxylated in various positions [5], but in man only one metabolite has been identified - the 17a-epimer [6].

The ratio of excreted trenbolone (17b-trenbolone) to epitrenbolone (17a-trenbolone) is estimated at 1:5 in a 24hr period [7].

What this means is that although Trenavar is a prohormone to trenbolone, it doesn't appear to be a significant metabolite in humans. The equilibrium of the reaction between 17-one and 17b-ol appears to be weighted heavily - in fact pretty much exclusively - in favour of the 17b-ol, so Trenavar should convert readily to the active form trenbolone. Once converted to trenbolone, it will be open to the same metabolism mechanisms as injectable tren - conversion via sulfatase to epitrenbolone and excretion as glucoronides.

Of course, this is largely conjecture, since neither trenbolone nor a precursor to it has ever been on the supplement market before... or has it?

A few years ago ALRI released an encapsulated product called "Methoxy TRN", advertised as containing "17b-methoxytrienbolone". This was quickly pulled from the shelves soon after its release, leaving only a few highly-collectable bottles and a reputation for tremendous strength and size gains and roadmap vascularity. This supplement was tested in 2008, and the researchers discovered the tell-tale mass spectra of trenbolone (and no sign of the advertised methoxy group) [8].

Detection Limits:

An anti-doping study from 1996 found that orally administered trenbolone was detectable by mass spectrometry for two to four days after a single administration, unlike injectable trenbolone, which is detectable for much longer [9]. The detection of trenbolone after administration of Trenavar is likely to follow similar lines, though detection methods may have improved since then. Athletes subjected to doping tests should of course avoid this and all other prohibited performance-enhancing products altogether.

Dosages and Cycle Durations:

Empirical evidence is the only way to determine this; once the product has been used by enough people we'll have a better idea of how much, and for how long, Trenavar is best used. However, due to recent logs it appears 15 mg two times per day is a good starting dose.

References:

[1] Steroids 74 (2009) 172–197
[2] Acta Endocrinologica, Vol 110, 1 Suppla, S129-S130
[3] J Steroid Biochem 1979;13:45–59.
[4] Toxicol Sci. 2002;70:202–211.
[5] Xenobiotica. 1981 Jul;11(7):489-500.
[6] Biol. Mass Spectrom. 20 (1991) 459–466.
[7] Recent advances in doping analysis (2). (1995) 269-274.
[8] Anal Chim Acta. 2009 Apr 1;637(1-2):92-100.
[9] Recent advances in doping analysis (3). (1996) 83-94.Share